Casey
Do³±czy³: 25 Cze 2021 Posty: 38
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What is a retinoid and what does it do? |
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Retinoids are considered the heroes of solving skin problems, especially acne problems. They also have anti-aging properties. Therefore, it is often used as an important ingredient in a variety of skin care products.
What is a retinoid and what does it do?
Retinoids are vitamin A derivatives. Retinoids can be found naturally, in food, and synthesized for use in many therapies. Most retinoids are bioactive by being absorbed through cell membranes and binding to the body. Receive RAR and RXR within the cell nucleus. It then becomes a compound that has many functions in regulating cell functions, such as modifying the expression of certain genes. or control the secretion of certain cytokines
The main function of the retinoid in the skin is to control the division and growth of the skin (epidermal differentiation) from the dermis to the epidermis. It also controls the shedding of epidermal cells both in normal conditions and when there is skin injury.
with these features A topical retinoid is therefore widely used and the main drug in the treatment of a number of skin diseases, such as acne, melasma, psoriasis, and some skin cancers.
What types of retinoids are in skin creams?
Isotretinoin and Tretinoin are the first topical retinoids. It has been used in the treatment of acne for over 50 years. It also helps slow down photoaging, brightens the skin, reduces dark spots, and helps heal existing scars. better Later, Adapalene was developed, a naphtoic acid derivative with retinoid-like properties. but works faster has a more stable structure and has fewer skin irritation effects than isotretinoin and topical tretinoin.
Adapalene has become widely used in the treatment of inflammatory acne and cystic acne. Next-generation topical retinoids, such as Alitretinoin and Bexarotene, are the primary treatments for Kaposi's sarcoma and cutaneous T-cell lymphoma, respectively. Tazarotene, a topical retinoid developed for the treatment of psoriasis, for example.
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Although retinoids are useful drugs It is widely accepted and used in clinical practice. But using topical retinoids can also have side effects. for example irritation erythema Flaky skin and sunburn, these side effects tend to gradually improve when combined with a moisturizing cream. In addition, topical use of retinoids may result in skin sensitivity. to more sunlight This may trigger certain types of sun-related diseases.
Retinoids are drugs with a wide range of biological effects and have long been used to treat skin diseases. Knowledge of side effects and comprehensive information about medication is essential for safe use. Should consult with a medical professional or pharmacist. for safe use
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